Searchable abstracts of presentations at key conferences in endocrinology

ea0094p111 | Reproductive Endocrinology | SFEBES2023

Immunometric and functional measurement of endogenous vasoinhibin in human sera

Zamora Magdalena , Harris David , Davies Nils , Ebnet Johannes , Radermacher Peter , Brucker Cosima , Waller Christiane , Pablo Robles Juan , Bertsch Thomas , Clapp Carmen , Triebel Jakob

Circulating levels of the antiangiogenic protein vasoinhibin (16 kDa PRL), a fragment of prolactin, are of interest in vasoproliferative retinopathies, preeclampsia, and peripartum cardiomyopathy, but are unknown due to the lack of a quantitative assay. Here, human serum samples were investigated for the concentration and bioactivity of vasoinhibin using a novel enzyme-linked immunosorbent assay (ELISA) for human vasoinhibin employing an anti-vasoinhibin monoclonal antibody, a...